Diagnosis and treatment of latent tuberculosis in patients with multiple sclerosis, expert consensus. On behalf of the Colombian Association of Neurology, Committee of Multiple Sclerosis

Diagnosis and treatment of latent tuberculosis in patients with multiple sclerosis, expert consensus.
On behalf of the Colombian Association of Neurology, Committee of Multiple Sclerosis

Abstract
Background: Multiple sclerosis is an inflammatory and neurodegenerative demyelinating disease.
Current treatment of multiple sclerosis focuses on the use of immunomodulatory, immunosuppressant,
and selective immunosuppressant agents. Some of these medications may result in high risk of opportunistic
infections including tuberculosis.

Objective: The purpose of this study was to obtain consensus from a panel of neurologists, pulmonologists,
infectious disease specialists, and epidemiology experts regarding the diagnosis, treatment, and
monitoring of latent tuberculosis in patients with multiple sclerosis.

Methods: A panel of experts in multiple sclerosis and tuberculosis was established. The methodological
process was performed in three phases: definition of questions, answer using Delphi methodology, and
the discussion of questions not agreed.

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